Southern Illinois University
2025 Football Schedule
Overall6-30.667
Conference3-20.600
StreakW2
Home3-1
Away3-2
Neutral0-0
| Date | Time | At | Opponent | Location | Tournament | Result |
|---|---|---|---|---|---|---|
| Aug 30 (Sat) | 6 PM | Home | Thomas More | Carbondale, IL (Saluki Stadium) | W 49-3 | |
| Sep 6 (Sat) | 6:30 PM (CT) | Away | Purdue | West Lafayette, IN | L 17-34 | |
| Sep 13 (Sat) | 6 PM | Away | UT Martin | Martin, TN | W 37-10 | |
| Sep 20 (Sat) | 6 PM | Away | Southeast Missouri State | Cape Girardeau, MO | W 59-31 | |
| Oct 4 (Sat) | 6 PM | Home | Indiana State | Carbondale, IL (Saluki Stadium) | W 55-27 | |
| Oct 11 (Sat) | 2:30 PM | Away | #1/#1 North Dakota State | Fargo, ND | L 17-45 | |
| Oct 18 (Sat) | 12 PM | Home | #9/#11 North Dakota | Carbondale, IL (Saluki Stadium) | Blackout Cancer | L 19-38 |
| Oct 25 (Sat) | 2 PM | Home | Northern Iowa | Carbondale, IL (Saluki Stadium) | W 31-17 | |
| Nov 1 (Sat) | 4 PM | Away | Murray State | Murray, KY | W 27-7 | |
| Nov 8 (Sat) | 1 PM (CT) | Away | #21/#22 Youngstown State | Youngstown, OH | - | |
| Nov 15 (Sat) | 12 PM | Home | #22/#25 South Dakota | Carbondale, IL (Saluki Stadium) | Senior Day / Military Appreciation | - |
| Nov 22 (Sat) | 12 PM | Away | #16/#17 Illinois State | Normal, IL | - |